Conolidine is usually a pure alkaloid derived within the bark with the tropical shrub Tabernaemontana divaricata, also known as crepe jasmine. This shrub was customarily used in Chinese, Ayurvedic, and Thai drugs, and is well-liked for its powerful ache-relieving Houses.Szpakowska et al. also analyzed conolidone and its action over the ACKR3 recept

Conolidine has distinctive features which might be beneficial for that administration of Persistent suffering. Conolidine is present in the bark on the flowering shrub T. divaricataThe primary asymmetric overall synthesis of conolidine was formulated by Micalizio and coworkers in 2011.[2] This artificial route lets usage of both enantiomer (mirror